Published on June 25, 2024–Updated on December 17, 2024
This EMBO Workshop brought together an interdisciplinary and diverse group of scientists discussing recent developments and cutting-edge advances in LD research. The meeting provided a unique platform for exchange between basic and clinical researchers across all career levels with ample opportunity for networking and career development.
About the Workshop
Lipid droplets (LDs) are major hubs in cellular and organismal metabolism that are highly conserved across species. Numerous cell biological and metabolic pathways converge at LDs to maintain energy and nutrient homeostasis. Their role in metabolic disorders such as type 2 diabetes, obesity, fatty liver and cardiovascular disease is undisputed. LDs are also important for host pathogen interaction, by supporting proliferation of infectious agents like viruses or bacteria, and are part of the innate immune system. However, the molecular mechanisms underlying the roles of LDs in health and disease are only beginning to emerge. A better understanding of key questions regarding the formation and consumption of LDs, as well as their functional and dynamic integration into cellular metabolism hold great promise to make inroads into the fascinating molecular world of the pathophysiology surrounding LDs.
Speakers from SPHERES :
Alenka COPIC, Session 4: Biophysics of LD Proteins, "Perilipin protein team gymnastics"
Chair: Joëlle BIGAY