I2MC Management
Dominique Langin
Principal Investigator;DVM PhD, UT Professor.
Dominique is the Principal Investigator of SPHERES; he supervises and coordinates the scientific work performed at UT3 for the SPHERES project.
Barbara Rieffly
PhD, SPHERES Project Manager; Project Management Officer, UT.Barbara coordinates the administrative and financial tasks of the project in close relationship with the Host Institution (UT3) and the European Commission.
Mouse Models
Geneviève Tavernier
PhD, CNRS Established Research Investigator.
Geneviève is specialist of mouse transgenesis, She supervises the creation of CRISPR-Cas9 mouse transgenic models.
Pierre-Damien Denechaud
PhD, Inserm Established Research Investigator.Pierre-Damien is expert in the metabolic phenotyping of mouse models. He analyses the systemic consequences of modifications in LD protein and lipid contents especially on the adipose tissue-liver crosstalk.
Etienne Mouisel
PhD, UT Associate Professor.Etienne is an animal physiologist. He is in charge of the follow-up of transgenic mice and metabolic phenotyping.
Khalil Acheikh Ibn Oumar
MSc, UT Technician.Khalil is a technician in molecular biology. He works for the embryo transfer service with Geneviève Tavernier.
Cell and molecular biology
Aline Mairal
MSc, Inserm Engineer.Aline is expert in molecular biology and cell metabolic studies. She develops new approaches for the study of adipocyte lipases.
Camille Bergoglio
MSc, UT Engineer.Camille is specialist in the expression of genes and proteins from adipocytes or murine and human adipose tissue. She participates in the study of lipases.
Laura Bottin
MSc, UT PhD student.Laura is working on human adipocytes engineered to produce various forms of hormone-sensitive lipase to study the role of the protein and also investigates the interactome of hormone-sensitive lipase in these cells.
Henrik Laurell
PhD, Inserm Established Research Investigator.Henrik brings his experience with TurboID as one of the first scientists using the system outside the original laboratory at Stanford University.
Marie-Adeline Marques
MSc, UT Engineer.Maria is expert in cell culture, LD imaging and clinical studies. She analyzes adipose tissue features and production.
Rémy Flores-Flores
MSc, Inserm Engineer.Remy is head of the imaging facility at I2MC. He supervises development in cell imaging.
Translational research
Pierre Gourdy
MD-PhD, UT Professor.Pierre is chief diabetologist, working on the translational relevance of cell and mouse data to humans. He brings expertise on sex differences and has links with Rydén’s lab.
Sylvie Caspar-Bauguil
PharmD-PhD, UT Associate Professor.Sylvie is specialist in medical biochemistry with expertise in lipidomics. She will contribute to the studies on lipid dynamics and interactions within large adipocyte LDs.
Eric Bieth
MD-PhD, UT Emeritus Professor.Eric is specialist in medical genetics. He brings expertise in interpretation of data on LD gene variants.
Other labs
Jean-Paul Concordet
PhD, Inserm Director of Research.
Jean-Paul is a specialist and head of a national facility on gene editing, He supervises design and in vitro assessment of CRISPR-Cas9 tools.
Audrey Ferrand
PhD, Inserm Established Research Investigator.
Audrey is long standing specialist in management of an organoid facility. She brings expertise in spheroid cultures.
Odile Schiltz
PhD, CNRS Director of Research.
Odile is head of the Proteomics platform at IPBS. She supervises proteomics analysis.
Jacques Rouquette
PhD, CNRS Research Engineer.
Jacques is head of core facilities at RESTORE unit. He supervises work using selective plane illumination microscopy.
Previous Fellows
Roxane Mégard
SPHERES Project manager.
Roxane was in charge of coordinating the administrative and financial tasks of the project. She left her position on March 14th 2022.
Eléna Griseti
PhD, Postdoctoral fellow.
Eléna is expert in human and mouse (from different genetic background) adipocytes spheroids culture and imaging. She investigated the role of perilipins in new cell models.
Stéphanie Cassant-Sourdy
MSc, UT Technician.Stéphanie brought her long-standing expertise in follow up and phenotyping of mouse transgenic lines.
Emilie Montastier-Simerman
MD-PhD, UT Professor.Emilie is a specialist in human nutrition. She worked on translational relevance of cell and mouse data to humans.
Marisol Vázquez Cuevas
PhD, SPHERES Project Manager; Project Management Officer, UT.
Marisol coordinated the administrative and financial tasks of the project in close relationship with the Host Institution (UT3) and the European Commission. She left her position on November 2023.
Clara Ferrier
MSc, technician.
Clara was in charge of genotyping and follow up of newly created transgenic mouse models.
Camille Fournes-Fraresso
MSc, UT PhD student.
Camille investigated the crosstalk between adipose tissue, liver and pancreas in mouse models lacking adipose triglyceride lipase and hormone-sensitive lipase in adipocytes.
Nathalie Viguerie
PhD, Inserm Established Research Investigator.Nathalie is expert in functional genomics and biostatistical analyses. She supervised panomics analyses.