I2MC Management
Dominique Langin
Principal Investigator;DVM PhD, UT3 Professor.
Dominique is the Principal Investigator of SPHERES; he supervises and coordinates the scientific work performed at UT3 for the SPHERES project.
Barbara Rieffly
PhD, SPHERES Project Manager; Project Management Officer, UT3.Barbara coordinates the administrative and financial tasks of the project in close relationship with the Host Institution (UT3) and the European Commission.
Mouse Models
Geneviève Tavernier
PhD, CNRS Established Research Investigator.
Specialist of mouse transgenesis, Geneviève supervises the creation of CRISPR-Cas9 mouse transgenic models.
Pierre-Damien Denechaud
PhD, Inserm Established Research Investigator.Expert in the metabolic phenotyping of mouse models, Pierre-Damien analyses the systemic consequences of modifications in LD protein and lipid contents especially on the adipose tissue-liver crosstalk.
Stéphanie Cassant-Sourdy
MSc, UT3 Technician.Thanks to long standing experience, Stéphanie brings her expertise in follow up and phenotyping of mouse transgenic lines.
Etienne Mouisel
PhD, UT3 Associate Professor.Animal physiologist, Etienne Mouisel is in charge of the follow-up of transgenic mice and metabolic phenotyping.
Khalil Acheikh Ibn Oumar
MSc, UT3 Technician.Technician in molecular biology, Khalil works for the embryo transfer service with Geneviève Tavernier.
MSc, UT3 PhD student.
Camille is investigating the crosstalk between adipose tissue and, liver and pancreas in mouse models lacking adipose triglyceride lipase and hormone-sensitive lipase in adipocytes.
Cell and molecular biology
Aline Mairal
MSc, Inserm Engineer.With expertise in molecular biology and cell metabolic studies, Aline develops new approaches for the study of adipocyte lipases.
Camille Bergoglio
MSc, UT3 Engineer.Thanks to her experience in the expression of genes and proteins from adipocytes or murine and human adipose tissue, Camille participates in the study of lipases.
Laura Bottin
MSc, UT3 PhD student.She is working on human adipocytes engineered to produce various forms of hormone-sensitive lipase to study the role of the protein and also investigates the interactome of hormone-sensitive lipase in these cells.
Henrik Laurell
PhD, Inserm Established Research Investigator.Henrik Laurell brings his experience with TurboID as one of the first scientists using the system outside the original laboratory at Stanford University.
Marie-Adeline Marques
MSc, UT3 Engineer.Thanks to experience in cell culture, LD imaging and clinical studies, Marie analyzes adipose tissue features and production.
Rémy Flores-Flores
MSc, Inserm Engineer.As head of the imaging facility at I2MC, Remy supervises development in cell imaging.
Translational research
Pierre Gourdy
MD-PhD, UT3 Professor.Chief diabetologist, working on the translational relevance of cell and mouse data to humans, Pierre brings expertise on sex differences and has links with Rydén’s lab.
Sylvie Caspar-Bauguil
PharmD-PhD, UT3 Associate Professor.Specialist in medical biochemistry with expertise in lipidomics, Sylvie will contribute to the studies on lipid dynamics and interactions within large adipocyte LDs.
Nathalie Viguerie
PhD, Inserm Established Research Investigator.Expert in functional genomics and biostatistical analyses, Nathalie supervises panomics analyses.
Eric Bieth
MD-PhD, UT3 Associate Professor.Specialist in medical genetics, Eric brings expertise in interpretation of data on LD gene variants.
Emilie Montastier-Simerman
MD-PhD, UT3 Professor.As specialist in human nutrition, Emilie works on translational relevance of cell and mouse data to humans.
Other labs
Jean-Paul Concordet
PhD, Inserm Director of Research.
As specialist and head of a national facility on gene editing, Jean-Paul supervises design and in vitro assessment of CRISPR-Cas9 tools.
Audrey Ferrand
PhD, Inserm Established Research Investigator.
Thanks to long standing experience and management of an organoid facility, Audrey brings expertise in spheroid cultures.
Odile Schiltz
PhD, CNRS Director of Research.
Head of the Proteomics platform at IPBS, Odile supervises proteomics analysis.
Jacques Rouquette
PhD, CNRS Research Engineer.
Head of core facilities at RESTORE unit, Jacques supervises work using selective plane illumination microscopy.
Previous Fellows
Roxane Mégard
SPHERES Project manager.
Roxane was in charge of coordinating the administrative and financial tasks of the project. She left her position on March 14th 2022.
Eléna Griseti
PhD, Postdoctoral fellow.
Eléna is expert in human and mouse (from different genetic background) adipocytes spheroids culture and imaging. She investigated the role of perilipins in new cell models.
Marisol Vázquez Cuevas
PhD, SPHERES Project Manager; Project Management Officer, UT3.
Marisol coordinated the administrative and financial tasks of the project in close relationship with the Host Institution (UT3) and the European Commission. She left her position on November 2023.
Clara Ferrier
MSc, technician.
Clara was in charge of genotyping and follow up of newly created transgenic mouse models.