Published on November 4, 2025 – Updated on November 4, 2025

J. Zhong, D. Zareifi, S. Weinbrenner, M. Hansen, F. Klingelhuber, P. A. Nono Nankam, S. Frendo-Cumbo, N. Bhalla, L. Cordeddu, T. de Castro Barbosa, P. Arner, I. Dahlman, M. Muniandy, S. Heinonen, K. H. Pietiläinen, A. Hoffmann, A. Ghosh, D. John, A. Tönjes, P. L. Ståhl , Y. Böttcher, M. Keller, P. Kovacs, A. G Kerr, D. Langin, C. Wolfrum, M. Blüher, N. Krahmer, L. Massier, N. Mejhert, M. Rydén (2025)

Abstract

We developed the Adipose Tissue Knowledge Portal by centralizing previously dispersed datasets, integrating clinical and experimental results with transcriptomic and proteomic data from >6,000 women and men. The platform includes multiple adipose depots, resident cell types, and adipocyte perturbation studies. By providing streamlined data access, the portal enables integrative analyses and serves as a powerful tool to interrogate various dimensions of adipose biology down to the single-cell level.